Open Positions

Open positions

We value and support our current students,faculty, and staff but also strive to grow as new students and faculty take interest in what we have to offer.

Review opportunites and open positions to join the MCB Community.


Cryo-EM Postdoctoral Fellow - Pallesen Lab

Indiana University is an equal employment and Affirmative Action Employer and a provider of ADA services. All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status or protected veteran status. Indiana University does not discriminate on the basis of sex in its educational programs and activities, including employment and admission, as required by Title IX. Questions or complaints regarding Title IX may be referred to the U.S. Department of Education Office for Civil Rights or the university Title IX Coordinator. See Indiana University’s Notice of Non-Discrimination here which includes contact information.

The Annual Security and Fire Safety Report, containing policy statements, crime and fire statistics for all Indiana University campuses, is available online. You may also request a physical copy by emailing IU Public Safety at iups@iu.edu 

Posting Details

Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation or identity, marital status, national origin, disability status or protected veteran status. Indiana University does not discriminate on the basis of sex in its educational programs and activities, including employment and admission, as required by Title IX. Indiana University’s non-discrimination statement is found in policy UA-01 at http://www.policies.iu.edu. Questions or complaints regarding Title IX may be referred to the U.S. Department of Education Office for Civil Rights or the university Title IX Coordinator. The address for Indiana University’s Title IX Coordinator is: 400 E. 7th Street, Poplars 833, Bloomington, IN 47405. The Annual Security and Fire Safety Report, containing policy statements, crime and fire statistics for all Indiana University campuses, is available online at https://protect.iu.edu/police-safety/annual-reports/index.html You may also request a physical copy by emailing IU Public Safety at iups@iu.edu or by visiting IUPD

Title Cryo-EM Postdoctoral Fellow - Pallesen Lab
Appointment Status Non-Tenure Track
Department IU Bloomington Biochemistry
Position Summary

The Pallesen Lab (https://cryoem.sitehost.iu.edu/) in the department of Molecular and Cellular Biochemistry at Indiana University Bloomington invites applications for a postdoctoral position. We are currently looking for candidates with emphasis on immunobiology and structural biology. Prior experience with cryo-electron microscopy (cryo-EM) is preferred. This is a two-year position with an immediate start date and possibility for extension.

The optimal candidate will perform high-resolution cryo-EM of coronavirus proteins in complex with animal and human antibodies. This project is fully extramurally funded and is a fast-paced consortium effort in collaboration with the Wistar Institute, Inovio, AstraZeneca and University of Pennsylvania. Publication opportunities in peer-reviewed scientific journals will be plenty. More info on our consortium can be found here: https://wistar.org/news/press-releases/darpa-and-jpeo-cbrnd-award-376m-wistar-institute-and-collaborators-inovio-0 and https://news.iu.edu/stories/2020/12/iub/releases/21-grant-to-develop-innovative-covid-19-treatment.html .

The Pallesen Lab studies molecular mechanisms of recognition and signal transfer in immunobiological interactions. We use a wealth of biochemical and biophysical techniques and our analyses revolve around state-of-the-art cryo-EM experimentation. We are pushing the envelope of cryo-EM structural characterization by implementing new and exciting methodologies into our workflows. Our lab is a RosettaCommons member and we have full access to our TFS Talos Arctica electron microscope equipped with phase plates and both TFS Falcon 3 and Gatan K3 direct electron detectors. We also have access to several extramural TFS Titan Krios instruments. Our structural studies rely on well-established collaborations as well as immunobiological systems and protein complexes that we optimize ourselves and express in our in-house bioreactor setup.

Indiana University Bloomington is a large, top-ranked public university with more than 40,000 students on its accoladed limestone campus. Our department has very strong, diverse and supportive virology and biochemistry communities. Our facilities are well-equipped and our group’s lab space is located in Simon Hall that was erected in 2007. The University has a strong athletics program competing in the Big10 conference and attracts many internationally acclaimed artists, musicians and dance companies to perform every year. Bloomington is a liberal and open-minded community located in the beautiful, forested rolling hills of Southern Indiana. Our town has a rich and diverse restaurant and nightlife scene and our surroundings offer countless outdoor activities such as waterskiing, kayaking, paddle-boarding and hiking.

Applications will be reviewed starting immediately and those received by April 19, 2021 will receive full consideration, but review will continue until the position is filled. The anticipated start date will be May 10, 2021 with the possibility to start sooner. Questions regarding the position or application process can be directed to: Charlie Fairns III, (cfairnsi@indiana.edu) or Professor Jesper Pallesen, (pallesen@indiana.edu).

Salary is commensurate with experience. The university offers excellent health insurance and benefits. Detailed benefit information can be found at http://hr.iu.edu/benefits/index.html#loaded.

The College of Arts and Sciences is committed to building and supporting a diverse, inclusive, and equitable community of students and scholars.

Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status or protected veteran status.

Basic Qualifications

Interested in candidates with a PhD by the start of appointment in biochemistry, biophysics, chemistry or related fields with relevant experience.

A strong background in biomolecular cryo-EM, protein expression and purification, and the characterization of immunobiological complexes is highly desirable. Candidates should be highly motivated, open to new approaches and techniques, and be able to tackle demanding challenges.

A completed application includes a curriculum vitae, and a brief summary of past research experience. The applicant should also arrange the submission of two or more recommendation letters.

Department Contact for Questions

Charlie Fairns III, (cfairnsi@indiana.edu) or Professor Jesper Pallesen, (pallesen@indiana.edu)

Additional Qualifications
Salary and Rank 45,000
Special Instructions
For Best Consideration Date 04/19/2021
Expected Start Date 05/10/2021
OAA # 22103-15

Supplemental Questions

Required fields are indicated with an asterisk (*).

Applicant Documents

Required Documents
  1. Curriculum Vitae
  2. Letter of Reference 1
  3. Letter of Reference 2
  4. Statement of Research and Teaching
Optional Documents

*********************************************************************************************

POSTDOCTROAL FELLOW POSITION IN: Bochman Lab, Indiana University, Bloomington

A full-time NIH-funded postdoctoral position is available in the lab of Dr. Matthew L. Bochman in the Molecular & Cellular Biochemistry Department at Indiana University in Bloomington, Indiana. The Bochman lab is interested in understanding the mechanistic functions of DNA helicases and associated proteins in the maintenance of genome integrity. They have ongoing projects focusing on: 1) defining the pathways of Fanconi Anemia-independent DNA inter-strand crosslink (ICL) repair, 2) the roles of RecQ and PIF1 family helicases in maintaining telomere length homeostasis, and 3) how post-translational modifications (PTMs) affect PIF1 helicase activities. The lab utilizes a variety of techniques in-house and through ongoing collaborations, including in vitro biochemistry, yeast genetics, next-generation sequencing, mass spectrometry, structural biology, click chemistry, and single-molecule biochemistry.

The postdoctoral researcher will have his/her choice of projects in the three areas listed above, access to hands-on experimental training from Dr. Bochman, his lab, and his collaborators, mentoring for fellowship applications and paper writing, and opportunities to mentor younger researchers.

A PhD in biochemistry, molecular biology, genetics, chemistry, or a related life sciences field is required. Experience with protein purification, using yeast as a model organism, in vitro enzymatic assays, and/or molecular cloning is preferred. Salary is commensurate with skills and level of experience, benefits included.

To apply for this position, please send a letter of application describing your interest, your CV, and the contact information for three references to https://indiana.peopleadmin.com/postings/9961. Information about the Bochman lab can be found at the link above, and you can find our recent publications here and preprints here.

Best consideration date is January 4, 2021. Exact start date is flexible.  Inquiries about the position can be directed to Matt Bochman (bochman@indiana.edu).

The College of Arts and Sciences is committed to building and supporting a diverse, inclusive, and equitable community of students and scholars.  Indiana University is an equal employment and affirmative action employer and a provider of ADA services.  All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status, or protected veteran status.

****************************************************************************************

 POSITION IN CHROMOSOME ARCHITECTURE:

(Steve D. Bell Lab, Indiana University, Bloomington)

A full-time NIH-funded postdoctoral position is available in Steve Bell’s lab, Department of Molecular and Cellular Biochemistry and Department of Biology, Indiana University, Bloomington. The lab conducts research on the machineries that effect DNA replication and sculpt genome conformation. We exploit a model organism, Sulfolobus to perform our work (see http://www.indiana.edu/~sbelllab/site/home.html).

The position is to investigate the function and architecture of the Sulfolobus genome. We have recently described the low-resolution structure of the Sulfolobus genome (Takemata et al., Cell, 2019). We will build on those preliminary data to determine the molecular basis of the establishment and maintenance of the compartmentalized genome architecture. Particular emphasis will be placed on the role of the novel SMC protein, coalescin, in establishing transcriptionally-repressed domains.

We seek a collegial, self-motivated, independent, and intellectually curious individual with a PhD in molecular biology, microbial genetics, biochemistry, or related field. Applicant for the position must have strong bench skills, and familiarity with techniques such as 3C and the bioinformatic analyses of next-gen sequencing data is required. In addition, candidates must have demonstrated written and oral communication skills. Experience working with archaea is helpful but not required. The position is initially available for 12 months, with possible extension for a further three years. Salary will be commensurate with experience, and full benefits are included.

To apply for the position (Chromosome architecture), please submit a letter of application indicating which position is being applied for, a CV, a statement of research interests, and the contact information for three references to https://indiana.peopleadmin.com/postings/8876.

Best consideration date is Dec.1, 2020. Exact start date is flexible.  Inquiries about the position can be directed to Steve Bell (stedbell@indiana.edu).

The College of Arts and Sciences is committed to building and supporting a diverse, inclusive, and equitable community of students and scholars.  Indiana University is an equal employment and affirmative action employer and a provider of ADA services.  All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status, or protected veteran status.

***************************************************************************************

Lab Technician III

For more information go to Jobs@IU search Job ID 292475

Molecular & Cellular BIOCHEMISTRY Dept. (BL-BIOC-IUBLA)

Department Information

Read more about the Physical and Biochemistry Facility (PBIF) here, and the Macromolecular Crystallography Facility (CAF) here!

Job Summary

This is technical and managerial work performing a variety of complex tasks related to the daily operations of the Physical and Biochemistry Facility (PBIF) and the Macromolecular Crystallography Facility (CAF). PBIF and CAF are located in Simon Hall MSB-1 science building receiving hundreds of users monthly. Both are equipped with state-of-the-art instrumentation, facilitating research for many groups in Biochemistry, Biology, and Chemistry Departments.

Support and assist a variety of research projects, jointly with the supervisor, by maintaining lab operations on a daily, weekly and monthly basis. Act as manager for PBIF - keep facility organized and ensure continuous operation. Perform scholarly research and train other personnel in PBIF (such as students) in standard techniques used in the lab. Assist users in experiments, automated and manual dispensing of commercial screens, crystallography screenings, sample preparation, crystal optimization, crystal harvesting, and data collection. Assist users in PBIF with experiments sample preparation and measurement. Perform data entry, organization and maintenance of files, upkeep of lab calendar, and monthly billing. Monitor and assess consumables inventory and order supplies as needed. Develop standard operating procedures for lab instrumentation and modify these procedures as appropriate. Monitor lab usage to ensure safe and efficient use of facilities.

There will be opportunities to participate in data interpretation and publication of the results.

Required Qualifications

Bachelor of Science degree in biology, biochemistry, chemistry, or a related discipline.

Good organization skills, with meticulous attention to detail and commitment to maintaining a clean and organized laboratory. Ability to work both independently and as part of a team. Excellent computational/data analysis skills. Excellent time management skills, and ability to be flexible with changes in daily or weekly tasks. Strong computer skills, including experience with Microsoft Office Suite and Dream Weaver.

Preferred Qualifications

Master's degree. One to five years of experience in structural biology.

The College of Arts and Sciences is committed to building and supporting a diverse, inclusive, and equitable community of students and scholars. Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All qualified applicants will receive consideration for employment without regard to age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status, or protected veteran status.

Diverse Faculty

We are growing, and now have 13 faculty at various ranks. Our faculty utilize a diverse range of model organisms to address a similarly broad range of interests including virus structure and infection processes, protein homeostasis, signal transduction, gene regulation and DNA repair and replication mechanisms.

Meet our faculty